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1.
Indian J Ophthalmol ; 2012 Mar; 60(2): 134-136
Article in English | IMSEAR | ID: sea-138808

ABSTRACT

We report a case of unilateral conjunctival ulcer due to Stenotrophomonas maltophilia infection in an immunocompetent individual. A 44-year-old male presented with complaints of pain and yellowish discharge in the right eye for one week. Patient underwent complete ophthalmic evaluation and relevant laboratory investigations. Anterior segment examination revealed localized conjunctival and episcleral congestion with conjunctival ulceration on the bulbar conjunctiva in the right eye. Gram's stain revealed gram-negative bacilli. Culture and sensitivity revealed S. maltophilia and responded well to topical moxifloxacin with systemic co-trimoxazole therapy.


Subject(s)
Adult , Anti-Infective Agents/therapeutic use , Aza Compounds/therapeutic use , Conjunctivitis/drug therapy , Conjunctivitis/microbiology , Conjunctivitis/pathology , Gram-Negative Bacterial Infections/complications , Gram-Negative Bacterial Infections/drug therapy , Gram-Negative Bacterial Infections/pathology , Humans , Male , Quinolines/therapeutic use , Stenotrophomonas maltophilia/isolation & purification , Ulcer/drug therapy , Ulcer/microbiology , Ulcer/microbiology
2.
Indian J Pathol Microbiol ; 2011 Apr-Jun 54(2): 254-257
Article in English | IMSEAR | ID: sea-141960

ABSTRACT

Background: Conjunctivitis of the newborn is defined as hyperemia and eye discharge in the neonates and is a common infection occurring in the neonates in the first month of life. In the United States, the incidence of neonatal conjunctivitis ranges from 1-2%, in India, the prevalence is 0.5-33% and varies in the world from 0.9-21% depending on the socioeconomic status. Aim: To study the organisms causing conjunctivitis of the newborn and to correlate the etiology with the mode of delivery. Design: Single center, prospective, observational study. Materials and Methods: A total of 300 mothers and their newborns, born over a period of one year, were included in the study. Of these 200 newborns were delivered through vaginal route (Group A) and 100 (Group B) delivered by lower segment caesarean section (LSCS). At the time of labour, high vaginal swabs were taken from the mothers. Two conjunctival swabs each from both eyes of the newborn were collected at birth and transported to Microbiology department in a candle jar immediately. Results: Eight babies in Group A, developed conjunctivitis at birth. None of the babies in Group B developed conjunctivitis, this difference was statistically highly significant (P<0.000). The organisms found in the conjunctiva of the newborns in Group A were Coagulase negative Staphylococcus, α hemolytic Streptococcus, Escherichia coli and Pseudomonas spps. However, the commonest organism leading to conjunctivitis in the newborn in this study was Coagulase negative Staphylococcus. It was observed that the mothers of 5 out of 8 babies (60%) developing conjunctivitis gave history of midwife interference and premature rupture of membranes so the presence of risk factors contribute to the occurrence of conjunctivitis in the newborn. Conclusions: It is inferred that the mode of delivery and the presence of risk factors is responsible for conjunctivitis in the newborn.


Subject(s)
Adult , Bacteria/classification , Bacteria/isolation & purification , Bacterial Infections/epidemiology , Bacterial Infections/microbiology , Conjunctiva/microbiology , Conjunctivitis/epidemiology , Conjunctivitis/microbiology , Female , Humans , India , Infant, Newborn , Prevalence , Prospective Studies , Risk Factors , United States , Vagina/microbiology
3.
Arq. bras. oftalmol ; 70(6): 924-928, nov.-dez. 2007. graf, tab
Article in Portuguese | LILACS | ID: lil-474095

ABSTRACT

OBJETIVO: Avaliar a suscetibilidade, in vitro, de Staphylococcus coagulase negativa (SCoN), isolados da conjuntiva e córnea, à meticilina, às fluoroquinolonas e aos aminoglicosídeos. MÉTODOS: Foram analisadas retrospectivamente 707 amostras oculares de SCoN quanto à suscetibilidade aos antimicrobianos pelo teste de disco difusão, durante o período de janeiro de 2000 a dezembro de 2003. RESULTADOS: Houve um aumento do número de SCoN em isolados da conjuntiva (n=57, ano de 2000 e n=153, ano de 2003) e da córnea (n=28, ano de 2000 e n=78, ano de 2003). A freqüência de SCoN resistentes à meticilina isolados da conjuntiva e da córnea, aumentou (1,8 a 19,6 por cento e 14,3 a 29,3 por cento respectivamente) durante o período avaliado. Não houve diferença estatisticamente significante nos anos estudados, nos percentuais de SCoN resistentes às fluoroquinolonas, nas conjuntivas (ofloxacina: 1,8 a 7,8 por cento e ciprofloxacina: 3,5 a 9,2 por cento) e nas córneas (ofloxacina: 14,3 a 9,0 por cento e ciprofloxacina:14,3 a 10,3 por cento). Avaliando-se os resultados das amostras isoladas da conjuntiva, observou-se um aumento na resistência à tobramicina: 15,8 a 34,6 por cento; e à gentamicina: 10,5 a 25,5 por cento; mas não houve mudança no perfil de resistência das amostras da córnea à tobramicina: 28,6 a 26,9 por cento e à gentamicina: 21,4 a 23,1 por cento). CONCLUSÃO: Houve diminuição na suscetibilidade in vitro dos SCoN para meticilina, tobramicina e gentamicina. As fluoroquinolonas, representadas pela ofloxacina e ciprofloxacina, demonstraram ter um padrão estável de suscetibilidade in vitro.


PURPOSE: To assess the in vitro susceptibility of conjunctival and corneal coagulase negative Staphylococcus (CoNS) to methicillin, fluoroquinolones and aminoglycosides. METHODS: A total of 707 conjunctival and corneal CoNS disk diffusion test results were retrospectively analyzed, from January 2000 through December 2003. RESULTS: From 2000 to 2003, there was an increase in number of CoNS isolated from conjunctiva (n=57 to n=153) and cornea (n=28 to n=78). The frequency of conjunctival and corneal methicillin-resistant CoNS also increased (1.8 to 19.6 percent and 14.3 to 29.3 percent, respectively). There was no statistically significant difference between fluoroquinolones-resistant CoNS percentages in conjunctiva (ofloxacin: 1.8 to 7.8 percent and ciprofloxacin: 3.5 to 9.2 percent) and cornea (ofloxacin: 14.3 to 9.0 percent and ciprofloxacin: 14.3 to 10.3 percent). Evaluating the results of the conjunctival samples, there was increased resistance to tobramycin (15.8 to 34.0 percent) and to gentamycin (10.5 to 25.5 percent). There was no change in resistance of corneal isolates to tobramycin (28.6 to 26.9 percent) and to gentamycin (21.4 to 23.1 percent). CONCLUSIONS: there was a decrease in in vitro CoNS susceptibility to methicillin, tobramycin and gentamycin. Fuoroquinolones represented by ofloxacin and ciprofloxacin demonstrated stable in vitro susceptibility.


Subject(s)
Humans , Anti-Bacterial Agents/pharmacology , Conjunctivitis/microbiology , Drug Resistance, Bacterial , In Vitro Techniques , Keratitis/microbiology , Staphylococcus/drug effects , Aminoglycosides/pharmacology , Chi-Square Distribution , Disk Diffusion Antimicrobial Tests , Fluoroquinolones/pharmacology , Retrospective Studies , Staphylococcus/enzymology , Time Factors
4.
Arq. bras. oftalmol ; 67(6): 897-900, nov.-dez. 2004. tab
Article in Portuguese | LILACS | ID: lil-393152

ABSTRACT

OBJETIVO: Abordar quatro casos de conjuntivite presumível por Acanthamoeba, descrevendo o diagnóstico, considerando sinais e sintomas e o tratamento instituído. MÉTODOS: Foram estudados casos de conjuntivite presumível por Acanthamoeba diagnosticados no Hospital de Olhos do Paraná (HOP), no período de setembro/1998 a janeiro/2002. Todos os olhos estudados foram submetidos a um protocolo de investigação que incluía exame oftalmológico completo, microbiologia e cultura de secreções conjuntivais. RESULTADOS: Os exames laboratoriais de microscopia e cultura do material colhido estes pacientes revelaram o diagnóstico de Acanthamoeba. A maioria dos pacientes referia olhos vermelhos e irritação ocular de longa data. Os autores encontraram correlação entre a cultura e o exame direto, em que se evidenciou a presença de cistos e trofozoítas do protozoário. CONCLUSAO: Este é o primeiro relato de conjuntivite provavelmente por Acanthamoeba de acordo com a literatura revisada. Pacientes selecionados e refratários ao tratamento habitual de infecção ocular externa devem ser considerados para estudo laboratorial adequado à procura etiológica da doença.


Subject(s)
Humans , Acanthamoeba/isolation & purification , Conjunctivitis/diagnosis , Conjunctivitis/microbiology , Conjunctivitis/therapy
5.
EMHJ-Eastern Mediterranean Health Journal. 1998; 4 (1): 44-49
in English | IMEMR | ID: emr-156502

ABSTRACT

Bacterial agents of ocular infection were studied in 485 children under 14 years of age from October 1993 to February 1995. Aerobic and anaerobic bacteriological methods and antimicrobial susceptibility testing were used. Conjunctivitis was the most common clinical feature [77.9%]. Bacterial agents were detected in the ocular samples of 66.8% of children and Staphylococcus aureus was the most common causative agent, being responsible for 28% of all cases. The frequency of ocular infection in patients aged 0-2 years was significantly higher than other age groups [P = 0.04]. Approximately 84% of all bacteria were sensitive to chloramphenicol


Subject(s)
Humans , Male , Female , Bacteria, Aerobic/pathogenicity , Bacteria, Anaerobic/pathogenicity , Conjunctivitis/microbiology , Microbial Sensitivity Tests/methods , Eye Infections, Bacterial/epidemiology , Child
6.
Article in English | IMSEAR | ID: sea-18353

ABSTRACT

Twenty seven Chlamydia trachomatis isolates from patients of conjunctivitis were tested for their in vitro sensitivities to ciprofloxacin and tetracycline in cyclohexamide treated McCoy cells on cover slip (shell vial) cultures. After a 48 h exposure of chlamydia infected monolayers to varying concentrations of each of the drugs, the cover slips were processed and stained for detection of major out membrane protein of C. trachomatis by fluorescent antibody test (FAT) using fluorescein conjugated monoclonal. Minimum inhibitory concentration (MIC90) and minimum lethal concentration (MLC90) of ciprofloxacin were 2.9 micrograms/ml and 5.7 micrograms/ml and for tetracycline 9.1 micrograms/ml and 18.0 micrograms/ml respectively. Ciprofloxacin may have a more promising role in treating chlamydial conjunctivitis than the commonly used tetracycline.


Subject(s)
Anti-Bacterial Agents/pharmacology , Anti-Infective Agents/pharmacology , Chlamydia trachomatis/drug effects , Ciprofloxacin/pharmacology , Conjunctivitis/microbiology , Humans , Microbial Sensitivity Tests , Tetracycline/pharmacology
7.
Rev. chil. infectol ; 13(4): 236-8, 1996.
Article in Spanish | LILACS | ID: lil-207400

ABSTRACT

An infant with meningococcal conjunctivitis is reported. In spite of intravenous penicillin and local treatment with chloramphenicol infection recurred after sixty days. Possible explanations are discussed and a review of literature related to risk of systemic disease after conjunctival infection is presented


Subject(s)
Humans , Male , Infant , Conjunctivitis/microbiology , Neisseria meningitidis/pathogenicity , Chloramphenicol/therapeutic use , Recurrence , Rifampin/therapeutic use
8.
Rev. cuba. oftalmol ; 5(2): 118-21, jul.-dic. 1992. tab
Article in Spanish | LILACS | ID: lil-120858

ABSTRACT

Se realiza un estudio microbiológico a 100 pacientes que padecen conjuntivitis crónica diagnosticados en la consulta de Oftalmología del Policlínico "Tomás Romay" de Artemisa para determinar la causa más frecuente. Se determinó que el Estafilococo aureus es el germen más frecuente productor de conjuntivitis crónica con el 43 % y que esta enfermedad tiene un predominio bilateral ya que se constató en el 50 %, en ambos ojos


Subject(s)
Infant, Newborn , Infant , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Humans , Conjunctivitis/etiology , Escherichia coli/isolation & purification , Klebsiella/isolation & purification , Proteus/isolation & purification , Pseudomonas/isolation & purification , Staphylococcus aureus/isolation & purification , Conjunctivitis/microbiology
9.
Joäo Pessoa; s.n; 1991. 110 p. tab.
Thesis in Portuguese | LILACS | ID: lil-232390

ABSTRACT

Este trabalho é o resultado de uma pesquisa laboratorial sobre a atividade antimicrobiana de estratos vegetais e óleos essenciais sobre bactérias causadoras de conjuntivite, realizada no Laboratório de Tecnologia Farmacêutica da Universidade Federal da Paraíba. Para execuçäo deste utilizou-se o método indutivo e a técnica laboratorial que permitiram a sistematizaçäo do trabalho e a posterior coleta de dados. Os resultados obtidos atestam um considerável poder antimicroniano dos produtos utilizados sobre algumas bactérias causadoras de conjuntivite. Consta também no corpo do trabalho, uma abordagem histórica sobre o uso das plantas medicinais através do tempo baseada na teoria do eterno retorno


Subject(s)
Humans , Male , Female , Conjunctivitis/microbiology , Conjunctivitis/therapy , Herbal Medicine , Oils, Volatile/pharmacology , Plant Extracts/pharmacology , Public Health Nursing
11.
Rev. Soc. Bras. Med. Trop ; 23(1): 33-6, jan.-mar. 1990. tab
Article in Portuguese | LILACS | ID: lil-97989

ABSTRACT

Setecentos e oitenta pacientes com recidivas clínicas de infecçäo conjuntivas ou queixas persistentes de prurido, ardor, dor, lacrimejamento e hiperemia, foram submetidos ao raspado conjuntival com citologia e pesquisa de inclusöes. Destes 247(31,7%) apresentaram inclusöes citoplasmáticas; 235 pacientes foram, também, submetidos a coloraçäo com anticorpo monoclonal fluorescente (imunofluorescência direta - DFA) com 90 (38,3%) casos positivos. Discute-se também, a importância do quadro clínico e dos métodos laboratoriais (coloraçäo com anticorpo monoclonal fluorescente e pesquisa de inclusöes citoplasmáticas). Os pacientes fazem parte de clientela de clínica particular e tem nível sócio-econômico de médio a alto


Subject(s)
Humans , Infant, Newborn , Infant , Child, Preschool , Child , Adult , Middle Aged , Adolescent , Conjunctivitis/microbiology , Eye Infections, Bacterial/epidemiology , Chlamydia Infections/epidemiology , Brazil , Cohort Studies , Hospitals, Private
12.
Rev. cuba. oftalmol ; 2(1/2): 55-63, ene.-ago. 1989. ilus, tab
Article in Spanish | LILACS | ID: lil-74731

ABSTRACT

Se realizó un estudio clínico, bacteriológico y microbiológico a 300 pacientes portadores de conjuntivitis. Se investigaron los primeros síntomas y signos y se encontró en primer término, secreción y sensación de cuerpo extraño. El exudado, el frotis conjuntival y la recogida de los datos clínicos por medio de una encuesta elaborada al efecto, demostró la correlación entre estos 3 exámenes y, por tanto, la importancia de los mismos en el diagnóstico de la conjuntivitis


Subject(s)
Humans , Conjunctivitis/microbiology
13.
Arq. bras. oftalmol ; 51(5): 194-6, 1988. tab
Article in Portuguese | LILACS | ID: lil-67283

ABSTRACT

Estudamos 509 casos de conjuntivite de provável etiologia bacteriana para avaliar o papel da análise laboratorial e sua correlaçäo clínica. Os autores apresentam os resultados obtidos nos exames citológico, bacterioscópico e de cultura, de amostras colhidas do saco conjuntival e pálpebras. Os sintomas, sinais clínicos e uso prévio de antibiótico, säo também apresentados. Analisando-se a sintomatologia, a secreçäo apareceu em 439 casos (89%) seguida por olho vermelho em 313 casos (61%) e lacrimejamento em 230 casos (45%). Em 395 casos (78.5%), os exames laboratoriais tiveram resultado etiológico conclusivo. O Staphylococcus aureus Z foi o agente isolado com maior freqüência, aparecendo em 350 casos (89%), predominando em todas as faixas etárias, seguido pelo Staphylococcus epidermidis em 22 casos (6%)


Subject(s)
Infant, Newborn , Infant , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Humans , Male , Female , Conjunctivitis/microbiology , Haemophilus influenzae/isolation & purification , Proteus mirabilis/isolation & purification , Pseudomonas aeruginosa/isolation & purification , Staphylococcus aureus/isolation & purification , Staphylococcus epidermidis/isolation & purification , Streptococcus pneumoniae/isolation & purification
15.
In. Fundaçäo Serviços de Saúde Pública. Instituto Evandro Chagas: 50 anos de contribuiçäo às ciências biológicas e à medicina tropical. s.l, Fundaçäo Serviços de Saúde Pública, 1986. p.659-71, ilus, tab.
Monography in Portuguese | LILACS | ID: lil-43457
16.
Rev. microbiol ; 16(1): 41-5, jan.-mar. 1985. tab
Article in Portuguese | LILACS | ID: lil-30481

ABSTRACT

Quarenta e cinco amostras de Staphylococcus aureus, isoladas de doentes com conjuntivite estafilocócica e de portadores säos, foram estudadas sob os seguintes aspectos: susceptibilidade a antimicrobianos e a fagos e produçäo de coagulase. Vinte das amostras foram do modelo de antibiograma RSSS de Barber e Burston e 16 do modelo RSSR. Näo houve correlaçäo entre fagótipo e tempo para coagulaçäo do plasma. Foi observada maior frequência de amostras com fagótipos do grupo III, sendo que nenhuma das amostras isoladas de secreçäo ocular foi fagotipável


Subject(s)
Humans , Staphylococcus aureus/isolation & purification , Conjunctivitis/microbiology , Staphylococcal Infections/microbiology , Bacteriophage Typing
19.
Rev. méd. Panamá ; 9(3): 176-81, sept. 1984. tab
Article in Spanish | LILACS | ID: lil-31940

ABSTRACT

Se informa el primer caso confirmado de radiculomielitis post-conjuntivitis hemorrágica aguda (CHA) ocurrido en Panamá y probablemente en el continente americano. Se describen sus características epidemiológicas, las manifestaciones clínicas y su diagnóstico virológico


Subject(s)
Adult , Humans , Female , Radiculopathy/microbiology , Conjunctivitis/microbiology , Enterovirus Infections/complications
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